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Using amlodipine and valsartan (Exforge)

Dear Patient,
Your health care provider has prescribed a combination product that contains amlodipine (a calcium channel blocker) and valsartan (an angiotensin II receptor blocker). These two medications act to lower your blood pressure in two different ways, making them more effective than either medication used alone. The brand name of this medication is Exforge.

How you’ll use Exforge
You’ll take Exforge once a day by mouth.

What to do if you miss a dose
If you forget a dose, take it as soon as you remember, then begin your usual routine the next day. Don’t make up missed doses. Don’t take more than one dose in any given day.

What to do about side effects
Notify your health care provider if you experience side effects to this medication.
Common: dizziness, swelling of the hand, feet and ankles, nasal congestion, sore throat and discomfort when swallowing, head or chest cold.
Less common: very low blood pressure, chest pain, allergic reaction.

What you must know about other medications
The risk of high potassium levels and heart failure is increased if this medication is taken with potassium sparing diuretics or angiotensin receptor blockers (ARBs). If this combination must be used, you'll need to be monitored very closely. Tell all of your health care providers that you're taking this medication.

Special directions

  • Take Exforge once daily at about the same time each day.
  • You’ll need periodic blood tests to check your blood potassium levels.

Keep in mind

  • This medication is associated with fetal injury and death. You should use contraception while you’re on this medication. If you think you’re pregnant or wish to become pregnant consult your health care provider.
  • It isn’t known how this medication could affect a breast-fed baby. Because of the potential for serious adverse effects on an infant, you should choose another method of feeding the baby while you’re taking this medication.
  • Report chest pain, dizziness, faintness, severe swelling.

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